Disease: Nicotine Dependence
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
THAS thoracoabdominal syndrome 0.560 0.808
COPD Pulmonary disease, chronic obstructive, severe early-onset 0.456 0.885
LINC02210-CRHR1 P34998 LINC02210-CRHR1 readthrough 0.570 0.692
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ANKK1 Q8NFD2 ankyrin repeat and kinase domain containing 1 Kinase 7.4E-12 0.604 0.462
OR2AG1 Q9H205 olfactory receptor family 2 subfamily AG member 1 (gene/pseudogene) G-protein coupled receptor 3.1E-11 0.582 0.808
FAAH O00519 fatty acid amide hydrolase 4.4E-11 0.545 0.692
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808
DBH P09172 dopamine beta-hydroxylase 3.3E-10 0.511 0.846
ALDH2 P05091 aldehyde dehydrogenase 2 family member Enzyme 3.4E-10 0.457 0.885
CD200R1 Q8TD46 CD200 receptor 1 4.3E-09 0.623 0.769
CYP2A6 P11509 cytochrome P450 family 2 subfamily A member 6 5.4E-09 0.556 0.731
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
CHRNA3 P32297 cholinergic receptor nicotinic alpha 3 subunit Ion channel 1.4E-07 0.588 0.692
TPH2 Q8IWU9 tryptophan hydroxylase 2 2.5E-07 0.546 0.654
ADH1B P00325 alcohol dehydrogenase 1B (class I), beta polypeptide Enzyme 9.9E-07 0.502 0.846
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885
CHRNA5 P30532 cholinergic receptor nicotinic alpha 5 subunit Ion channel 2.1E-06 0.593 0.577
GAL P22466 galanin and GMAP prepropeptide 4.4E-06 0.493 0.846
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.8E-05 0.517 0.769
OPRK1 P41145 opioid receptor kappa 1 G-protein coupled receptor 4.1E-05 0.555 0.615
KMO O15229 kynurenine 3-monooxygenase 4.8E-05 0.674 0.615
CHRNA4 P43681 cholinergic receptor nicotinic alpha 4 subunit Ion channel 8.5E-05 0.492 0.808
TAAR1 Q96RJ0 trace amine associated receptor 1 G-protein coupled receptor 3.9E-04 0.682 0.423