| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
|---|---|---|---|---|---|---|
| APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
| NOS3 | P29474 | nitric oxide synthase 3 | 6.7E-07 | 0.378 | 0.885 | |
| MPO | P05164 | myeloperoxidase | Enzyme | 7.1E-15 | 0.377 | 0.923 |
| APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
| MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
| PLAU | P00749 | plasminogen activator, urokinase | Enzyme | 2.3E-06 | 0.425 | 0.923 |
| PRNP | F7VJQ1 P04156 | prion protein | 6.3E-04 | 0.445 | 0.923 | |
| HFE | Q30201 | homeostatic iron regulator | 2.6E-08 | 0.436 | 0.846 | |
| GRN | P28799 | granulin precursor | 7.0E-02 | 0.435 | 0.846 | |
| PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
| PLA2G6 | O60733 | phospholipase A2 group VI | Enzyme modulator | 2.5E-10 | 0.476 | 0.846 |
| TREM2 | Q9NZC2 | triggering receptor expressed on myeloid cells 2 | 3.3E-09 | 0.519 | 0.769 | |
| NPC1 | O15118 | NPC intracellular cholesterol transporter 1 | Transporter | 6.5E-06 | 0.518 | 0.692 |
| A2M | P01023 | alpha-2-macroglobulin | Enzyme modulator | 4.5E-11 | 0.529 | 0.769 |
| PSEN2 | P49810 | presenilin 2 | Enzyme | 5.4E-04 | 0.550 | 0.654 |
| TOMM40 | O96008 | translocase of outer mitochondrial membrane 40 | Transporter | 0.99 | 0.590 | 0.538 |
| SORL1 | Q92673 | sortilin related receptor 1 | Transporter | 7.7E-11 | 0.582 | 0.692 |
| NPC2 | P61916 | NPC intracellular cholesterol transporter 2 | 1.8E-03 | 0.612 | 0.769 | |
| ITM2B | Q9Y287 | integral membrane protein 2B | 0.63 | 0.617 | 0.654 | |
| VPS13C | Q709C8 | vacuolar protein sorting 13 homolog C | 7.6E-49 | 0.653 | 0.346 | |
| ABCA7 | Q8IZY2 | ATP binding cassette subfamily A member 7 | Transporter | 2.1E-55 | 0.644 | 0.577 |