Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
ACE | P12821 | angiotensin I converting enzyme | Enzyme | 1.0E-37 | 0.328 | 0.923 |
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
EGF | P01133 | epidermal growth factor | 8.5E-17 | 0.357 | 0.923 | |
PCNA | P12004 | proliferating cell nuclear antigen | Nucleic acid binding | 0.98 | 0.382 | 0.846 |
ELN | P15502 | elastin | 2.1E-14 | 0.415 | 0.885 | |
CASR | P41180 | calcium sensing receptor | G-protein coupled receptor | 4.7E-02 | 0.410 | 0.846 |
ATN1 | P54259 | atrophin 1 | 1.00 | 0.409 | 0.885 | |
CFTR | P13569 | CF transmembrane conductance regulator | Ion channel | 2.2E-58 | 0.424 | 0.885 |
SMAD3 | P84022 | SMAD family member 3 | Transcription factor | 0.80 | 0.415 | 0.923 |
TSC2 | P49815 | TSC complex subunit 2 | Enzyme modulator | 1.00 | 0.439 | 0.808 |
AFP | P02771 | alpha fetoprotein | Transporter | 1.1E-11 | 0.429 | 0.885 |
TSC1 | Q92574 | TSC complex subunit 1 | 1.00 | 0.440 | 0.808 | |
ARID1A | O14497 | AT-rich interaction domain 1A | 1.00 | 0.455 | 0.846 | |
P2RX7 | Q99572 | purinergic receptor P2X 7 | Ion channel | 3.3E-11 | 0.450 | 0.808 |
HNF1B | P35680 | HNF1 homeobox B | Nucleic acid binding | 1.00 | 0.473 | 0.808 |
AQP1 | P29972 | aquaporin 1 (Colton blood group) | Ion channel | 2.6E-07 | 0.467 | 0.885 |
SRC | P12931 | SRC proto-oncogene, non-receptor tyrosine kinase | Kinase | 1.00 | 0.467 | 0.885 |
PKD1 | P98161 | polycystin 1, transient receptor potential channel interacting | 1.00 | 0.493 | 0.769 | |
TMEM67 | Q5HYA8 | transmembrane protein 67 | 2.1E-24 | 0.512 | 0.769 | |
EPHA3 | P29320 | EPH receptor A3 | Kinase | 1.2E-05 | 0.497 | 0.692 |