Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
ACE | P12821 | angiotensin I converting enzyme | Enzyme | 1.0E-37 | 0.328 | 0.923 |
LEP | P41159 | leptin | 0.46 | 0.349 | 0.846 | |
AGT | P01019 | angiotensinogen | Enzyme modulator | 5.0E-08 | 0.367 | 0.923 |
COMT | P21964 | catechol-O-methyltransferase | Enzyme | 1.1E-06 | 0.400 | 0.923 |
RET | P07949 | ret proto-oncogene | Kinase | 1.00 | 0.392 | 0.885 |
SNCA | P37840 | synuclein alpha | Transporter | 0.88 | 0.427 | 0.885 |
SLC6A4 | P31645 | solute carrier family 6 member 4 | Transporter | 0.25 | 0.429 | 0.808 |
DRD2 | P14416 | dopamine receptor D2 | G-protein coupled receptor | 0.75 | 0.436 | 0.846 |
CYP2D6 | P10635 | cytochrome P450 family 2 subfamily D member 6 | 1.1E-25 | 0.437 | 0.885 | |
PRKN | O60260 | parkin RBR E3 ubiquitin protein ligase | Enzyme | 6.9E-07 | 0.431 | 0.846 |
INS | P01308 | insulin | 0.30 | 0.445 | 0.923 | |
VHL | P40337 | von Hippel-Lindau tumor suppressor | Enzyme | 8.0E-02 | 0.443 | 0.846 |
COPD | Pulmonary disease, chronic obstructive, severe early-onset | 0.456 | 0.885 | |||
SDHD | O14521 | succinate dehydrogenase complex subunit D | Transporter | 0.34 | 0.472 | 0.885 |
CCK | P06307 | cholecystokinin | 3.3E-05 | 0.453 | 0.846 | |
SDHB | P21912 | succinate dehydrogenase complex iron sulfur subunit B | Enzyme | 2.4E-04 | 0.474 | 0.846 |
MAOA | P21397 | monoamine oxidase A | 1.00 | 0.465 | 0.769 | |
KRT7 | P08729 | keratin 7 | 3.1E-12 | 0.463 | 0.808 | |
SNAP25 | P60880 | synaptosome associated protein 25 | Transporter | 0.99 | 0.489 | 0.808 |
UCHL1 | P09936 | ubiquitin C-terminal hydrolase L1 | Enzyme | 0.99 | 0.482 | 0.885 |
SDHA | P31040 | succinate dehydrogenase complex flavoprotein subunit A | Enzyme | 2.6E-10 | 0.517 | 0.731 |
IGFBP2 | P18065 | insulin like growth factor binding protein 2 | Enzyme modulator | 0.12 | 0.478 | 0.769 |
FH | P07954 | fumarate hydratase | Enzyme | 8.8E-02 | 0.489 | 0.846 |
LRRK2 | Q5S007 | leucine rich repeat kinase 2 | Kinase | 2.6E-30 | 0.510 | 0.808 |