Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
LEP P41159 leptin 0.46 0.349 0.846
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
INS P01308 insulin 0.30 0.445 0.923
VHL P40337 von Hippel-Lindau tumor suppressor Enzyme 8.0E-02 0.443 0.846
COPD Pulmonary disease, chronic obstructive, severe early-onset 0.456 0.885
SDHD O14521 succinate dehydrogenase complex subunit D Transporter 0.34 0.472 0.885
CCK P06307 cholecystokinin 3.3E-05 0.453 0.846
SDHB P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 2.4E-04 0.474 0.846
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
KRT7 P08729 keratin 7 3.1E-12 0.463 0.808
SNAP25 P60880 synaptosome associated protein 25 Transporter 0.99 0.489 0.808
UCHL1 P09936 ubiquitin C-terminal hydrolase L1 Enzyme 0.99 0.482 0.885
SDHA P31040 succinate dehydrogenase complex flavoprotein subunit A Enzyme 2.6E-10 0.517 0.731
IGFBP2 P18065 insulin like growth factor binding protein 2 Enzyme modulator 0.12 0.478 0.769
FH P07954 fumarate hydratase Enzyme 8.8E-02 0.489 0.846
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808