Disease: Nicotine Dependence
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ADH1B P00325 alcohol dehydrogenase 1B (class I), beta polypeptide Enzyme 9.9E-07 0.502 0.846
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CCK P06307 cholecystokinin 3.3E-05 0.453 0.846
CHRNA3 P32297 cholinergic receptor nicotinic alpha 3 subunit Ion channel 1.4E-07 0.588 0.692
CHRNA4 P43681 cholinergic receptor nicotinic alpha 4 subunit Ion channel 8.5E-05 0.492 0.808
CHRNA5 P30532 cholinergic receptor nicotinic alpha 5 subunit Ion channel 2.1E-06 0.593 0.577
CHRNA6 Q15825 cholinergic receptor nicotinic alpha 6 subunit Ion channel 3.6E-08 0.711 0.346
CHRNA7 P36544 Q494W8 cholinergic receptor nicotinic alpha 7 subunit Ion channel 4.2E-04 0.532 0.654
CHRNB2 P17787 cholinergic receptor nicotinic beta 2 subunit Ion channel 7.3E-04 0.617 0.308
CHRNB4 P30926 cholinergic receptor nicotinic beta 4 subunit Ion channel 0.14 0.644 0.423
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.8E-05 0.517 0.769
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
CYP2A6 P11509 cytochrome P450 family 2 subfamily A member 6 5.4E-09 0.556 0.731
CYP2B6 P20813 cytochrome P450 family 2 subfamily B member 6 1.9E-10 0.428 0.846
DBH P09172 dopamine beta-hydroxylase 3.3E-10 0.511 0.846
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
FAAH O00519 fatty acid amide hydrolase 4.4E-11 0.545 0.692
GRM2 Q14416 glutamate metabotropic receptor 2 G-protein coupled receptor 0.12 0.582 0.577
HCRT O43612 hypocretin neuropeptide precursor 2.9E-02 0.500 0.808
LINC02210-CRHR1 P34998 LINC02210-CRHR1 readthrough 0.570 0.692
NPY2R P49146 neuropeptide Y receptor Y2 G-protein coupled receptor 3.6E-02 0.612 0.577