Disease: Endothelial dysfunction
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
FBN2 P35556 fibrillin 2 Calcium-binding protein 1.00 0.505 0.808
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
PRKCB P05771 protein kinase C beta Kinase 1.00 0.453 0.885
ROCK1 Q13464 Rho associated coiled-coil containing protein kinase 1 Kinase 1.00 0.513 0.731
ROCK2 O75116 Rho associated coiled-coil containing protein kinase 2 Kinase 1.00 0.529 0.808
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
GRK2 P25098 G protein-coupled receptor kinase 2 Kinase 1.00 0.532 0.654
THBS1 P07996 thrombospondin 1 1.00 0.407 0.885
RELA Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 1.00 0.406 0.885
LMNA P02545 lamin A/C 1.00 0.384 0.885
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
CYBB P04839 cytochrome b-245 beta chain Ion channel 1.00 0.452 0.885
MAPK8 P45983 mitogen-activated protein kinase 8 Kinase 1.00 0.397 0.885
ACE2 Q9BYF1 angiotensin I converting enzyme 2 Enzyme 1.00 0.477 0.769
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885
GLA P06280 galactosidase alpha 1.00 0.537 0.769
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PPARD Q03181 peroxisome proliferator activated receptor delta Nuclear receptor 0.99 0.513 0.846
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808
STK11 Q15831 serine/threonine kinase 11 Kinase 0.99 0.435 0.808
EDNRA P25101 endothelin receptor type A G-protein coupled receptor 0.99 0.426 0.885
RAPGEF5 Q92565 Rap guanine nucleotide exchange factor 5 Enzyme modulator 0.98 0.524 0.769
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962