Disease: Thrombophilia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
F3 P13726 coagulation factor III, tissue factor Receptor 1.9E-02 0.415 0.846
F5 P12259 coagulation factor V Enzyme 5.9E-15 0.441 0.846
F8 P00451 coagulation factor VIII Enzyme 1.00 0.542 0.769
F9 P00740 coagulation factor IX Enzyme 1.00 0.465 0.885
FGA P02671 fibrinogen alpha chain 1.2E-13 0.573 0.769
FGB P02675 fibrinogen beta chain Signaling 0.57 0.584 0.692
HABP2 Q14520 hyaluronan binding protein 2 Enzyme 2.0E-15 0.593 0.615
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923
HRG P04196 histidine rich glycoprotein Enzyme modulator 5.9E-14 0.603 0.577
IFNA1 P01562 interferon alpha 1 0.371 0.923
IFNA13 P01562 interferon alpha 13 0.374 0.923
IFNG P01579 interferon gamma 0.47 0.288 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
ITGB3 P05106 integrin subunit beta 3 Receptor 1.7E-03 0.485 0.846
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
LPA P08519 lipoprotein(a) Enzyme 6.6E-89 0.444 0.769
MARCHF1 Q8TCQ1 membrane associated ring-CH-type finger 1 8.7E-03 0.540 0.808
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
MTRR Q9UBK8 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 2.2E-14 0.502 0.808
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
PADI4 Q9UM07 peptidyl arginine deiminase 4 4.6E-16 0.494 0.808
PC P11498 pyruvate carboxylase Enzyme 1.4E-02 0.515 0.808
PLAT P00750 plasminogen activator, tissue type Enzyme 5.7E-05 0.445 0.885
PLG P00747 plasminogen Enzyme 1.0E-02 0.389 0.923
PPP1R3B Q86XI6 protein phosphatase 1 regulatory subunit 3B Enzyme modulator 6.5E-02 0.686 0.462