Disease: Ichthyosis, X-Linked
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ALB P02768 albumin Transporter 0.64 0.317 0.962
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808
IL6 P05231 interleukin 6 0.32 0.248 0.962
KRT20 P35900 keratin 20 9.1E-11 0.388 0.846
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885
MIB1 Q86YT6 mindbomb E3 ubiquitin protein ligase 1 Enzyme 3.4E-88 0.438 0.769
MKI67 P46013 marker of proliferation Ki-67 1.3E-28 0.431 0.808
MLRL Myeloid leukemia-related gene (myeloid tumor suppressor) 0.564 0.769
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
NME1 P15531 NME/NM23 nucleoside diphosphate kinase 1 Kinase 3.2E-03 0.443 0.808
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
SETD2 Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 1.00 0.424 0.846
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
TIMM8A O60220 translocase of inner mitochondrial membrane 8A 0.65 0.510 0.846