TP53 |
P04637
|
tumor protein p53
|
Transcription factor
|
0.53 |
0.236 |
0.962 |
PIK3CA |
P42336
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
|
Kinase
|
1.00 |
0.292 |
0.923 |
CTNNB1 |
P35222
|
catenin beta 1
|
|
1.00 |
0.303 |
0.885 |
PTEN |
P60484
|
phosphatase and tensin homolog
|
Enzyme
|
0.26 |
0.305 |
0.923 |
BRAF |
P15056
|
B-Raf proto-oncogene, serine/threonine kinase
|
Kinase
|
1.00 |
0.319 |
0.846 |
KRAS |
P01116
|
KRAS proto-oncogene, GTPase
|
Enzyme modulator
|
7.9E-04 |
0.320 |
0.923 |
ERBB2 |
P04626
|
erb-b2 receptor tyrosine kinase 2
|
Kinase
|
6.0E-03 |
0.328 |
0.923 |
MTOR |
P42345
|
mechanistic target of rapamycin kinase
|
Kinase
|
1.00 |
0.343 |
0.885 |
NFE2L2 |
Q16236
|
nuclear factor, erythroid 2 like 2
|
Enzyme
|
3.6E-03 |
0.357 |
0.885 |
FGFR2 |
P21802
|
fibroblast growth factor receptor 2
|
Kinase
|
1.00 |
0.380 |
0.808 |
HRAS |
P01112
|
HRas proto-oncogene, GTPase
|
Enzyme modulator
|
8.0E-02 |
0.378 |
0.885 |
NRAS |
P01111
|
NRAS proto-oncogene, GTPase
|
Enzyme modulator
|
0.49 |
0.390 |
0.808 |
RAC1 |
P63000
|
Rac family small GTPase 1
|
Enzyme modulator
|
0.76 |
0.429 |
0.962 |
MAP2K1 |
Q02750
|
mitogen-activated protein kinase kinase 1
|
Kinase
|
0.90 |
0.439 |
0.846 |
ERBB3 |
P21860
|
erb-b2 receptor tyrosine kinase 3
|
Kinase
|
1.7E-15 |
0.448 |
0.808 |
MYCN |
P04198
|
MYCN proto-oncogene, bHLH transcription factor
|
Transcription factor
|
0.89 |
0.454 |
0.808 |
PIK3R1 |
P27986
|
phosphoinositide-3-kinase regulatory subunit 1
|
Kinase
|
1.00 |
0.477 |
0.885 |
SOS1 |
Q07889
|
SOS Ras/Rac guanine nucleotide exchange factor 1
|
Enzyme modulator
|
1.00 |
0.485 |
0.808 |
FBXW7 |
Q969H0
|
F-box and WD repeat domain containing 7
|
Enzyme modulator
|
1.00 |
0.465 |
0.808 |
XPO1 |
O14980
|
exportin 1
|
Receptor
|
1.00 |
0.504 |
0.692 |
POLE |
Q07864
|
DNA polymerase epsilon, catalytic subunit
|
|
8.0E-27 |
0.526 |
0.731 |
PPP2R1A |
P30153
|
protein phosphatase 2 scaffold subunit Aalpha
|
Enzyme
|
0.98 |
0.588 |
0.577 |
SPOP |
O43791
|
speckle type BTB/POZ protein
|
|
1.00 |
0.597 |
0.500 |
U2AF1 |
P0DN76 Q01081
|
U2 small nuclear RNA auxiliary factor 1
|
Nucleic acid binding
|
0.99 |
0.604 |
0.577 |
RHEB |
Q15382
|
Ras homolog, mTORC1 binding
|
Enzyme modulator
|
0.98 |
0.631 |
0.577 |