Disease: Congenital arteriovenous malformation
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
ACVRL1 P37023 activin A receptor like type 1 Kinase 9.7E-04 0.493 0.769
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ANGPT2 O15123 angiopoietin 2 Signaling 0.83 0.410 0.846
ARL6IP6 Q8N6S5 ADP ribosylation factor like GTPase 6 interacting protein 6 1.8E-02 0.686 0.615
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
ELN P15502 elastin 2.1E-14 0.415 0.885
ENG P17813 endoglin 1.00 0.446 0.846
EPHB4 P54760 EPH receptor B4 Kinase 1.3E-02 0.524 0.692
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923
GDF2 Q9UK05 growth differentiation factor 2 Signaling 2.5E-03 0.529 0.731
GNAQ P50148 G protein subunit alpha q Enzyme modulator 0.98 0.516 0.808
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
NES P48681 nestin 1.6E-06 0.450 0.808
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
RASA1 P20936 RAS p21 protein activator 1 Enzyme modulator 1.00 0.481 0.885
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808
TEK Q02763 TEK receptor tyrosine kinase Kinase 1.00 0.462 0.692
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923