Disease: Amyotrophic Lateral Sclerosis, Familial
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CASP1 P29466 caspase 1 Enzyme 3.5E-05 0.413 0.885
CD2AP Q9Y5K6 CD2 associated protein 0.23 0.558 0.731
CLU P10909 clusterin 7.8E-05 0.426 0.885
CRYAB P02511 crystallin alpha B 2.2E-02 0.515 0.731
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
CYBB P04839 cytochrome b-245 beta chain Ion channel 1.00 0.452 0.885
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
LGALS1 P09382 galectin 1 Signaling 4.5E-03 0.435 0.846
LINC01672 long intergenic non-protein coding RNA 1672 0.462 0.846
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
P4HB P07237 prolyl 4-hydroxylase subunit beta 1.00 0.488 0.808
PRDX2 P32119 peroxiredoxin 2 Enzyme 8.7E-02 0.474 0.885
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
SERPINA3 P01011 serpin family A member 3 Enzyme modulator 8.8E-14 0.486 0.846
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962