Disease: Optic Atrophy, Hereditary, Leber
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
CYTB P00156 cytochrome b 0.529 0.808
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
NPTX2 P47972 neuronal pentraxin 2 3.1E-02 0.617 0.615
OPA1 O60313 OPA1 mitochondrial dynamin like GTPase Enzyme modulator 0.99 0.510 0.846
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
RNR2 Q8IVG9 l-rRNA 0.603 0.692
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
TFAM Q00059 transcription factor A, mitochondrial 0.17 0.529 0.731
TK2 O00142 thymidine kinase 2 Kinase 3.9E-07 0.585 0.615
TRNK tRNA 0.608 0.577
TWNK Q96RR1 twinkle mtDNA helicase Enzyme 3.2E-03 0.516 0.692