Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
LMNA P02545 lamin A/C 1.00 0.384 0.885
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
HMGA2 P52926 high mobility group AT-hook 2 Nucleic acid binding 0.87 0.429 0.808
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808
SDHB P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 2.4E-04 0.474 0.846
ZMPSTE24 O75844 zinc metallopeptidase STE24 Enzyme 8.9E-16 0.517 0.731
IL12A P29459 interleukin 12A 4.7E-02 0.491 0.808
KITLG P21583 KIT ligand 0.85 0.473 0.885
IRF5 Q13568 interferon regulatory factor 5 Transcription factor 9.0E-03 0.489 0.731
NR0B1 P51843 nuclear receptor subfamily 0 group B member 1 Nuclear receptor 0.97 0.494 0.808
GNAQ P50148 G protein subunit alpha q Enzyme modulator 0.98 0.516 0.808
FANCC Q00597 FA complementation group C 2.8E-13 0.507 0.808