Disease: Familial (FPAH)
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CDKN2B-AS1 CDKN2B antisense RNA 1 0.491 0.769
KRIT1 O00522 KRIT1 ankyrin repeat containing 6.9E-04 0.500 0.808
NPC1 O15118 NPC intracellular cholesterol transporter 1 Transporter 6.5E-06 0.518 0.692
CLOCK O15516 clock circadian regulator 1.00 0.463 0.885
UGT1A9 O60656 UDP glucuronosyltransferase family 1 member A9 5.4E-08 0.590 0.577
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
ABCA1 O95477 ATP binding cassette subfamily A member 1 Transporter 1.5E-13 0.467 0.846
ADCY5 O95622 adenylate cyclase 5 1.00 0.617 0.577
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885
IL2RA P01589 interleukin 2 receptor subunit alpha Receptor 5.5E-02 0.389 0.885
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885
HLA-DQA1 P01909 major histocompatibility complex, class II, DQ alpha 1 Immune response 2.4E-02 0.416 0.846
COL4A1 P02462 collagen type IV alpha 1 chain 1.00 0.484 0.731
APOA1 P02647 apolipoprotein A1 5.5E-04 0.429 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692
APOB P04114 apolipoprotein B 1.9E-16 0.453 0.808
LCAT P04180 lecithin-cholesterol acyltransferase Enzyme 8.1E-02 0.588 0.654
VWF P04275 von Willebrand factor Enzyme modulator 3.2E-25 0.408 0.885
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
CYP1A2 P05177 cytochrome P450 family 1 subfamily A member 2 Enzyme 2.5E-10 0.494 0.923
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962