Disease: Dyslipidemias
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
DNAH11 Q96DT5 dynein axonemal heavy chain 11 Enzyme 2.5E-58 0.587 0.692
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
FADS1 O60427 fatty acid desaturase 1 0.37 0.582 0.769
FADS2 O95864 fatty acid desaturase 2 1.00 0.575 0.692
FGF21 Q9NSA1 fibroblast growth factor 21 Signaling 2.9E-02 0.485 0.769
FTO Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 8.4E-08 0.486 0.885
GALNT2 Q10471 polypeptide N-acetylgalactosaminyltransferase 2 Enzyme 8.4E-03 0.678 0.538
GCK P35557 glucokinase Kinase 0.63 0.523 0.808
GCKR Q14397 glucokinase regulator 8.5E-19 0.604 0.615
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846
LCAT P04180 lecithin-cholesterol acyltransferase Enzyme 8.1E-02 0.588 0.654
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885
LEPR P48357 leptin receptor Signaling 0.99 0.433 0.808
LIPC P11150 lipase C, hepatic type Enzyme 3.3E-07 0.585 0.654
LPA P08519 lipoprotein(a) Enzyme 6.6E-89 0.444 0.769
LPAL2 Q16609 lipoprotein(a) like 2, pseudogene Enzyme 0.626 0.731
LPL P06858 lipoprotein lipase Enzyme 1.3E-09 0.474 0.808
MACO1 Q8N5G2 macoilin 1 1.00 1.000 0.038
MLXIPL Q9NP71 MLX interacting protein like 4.8E-02 0.554 0.731
MSRA Q9UJ68 methionine sulfoxide reductase A Enzyme 1.5E-15 0.608 0.615
NECTIN2 Q92692 nectin cell adhesion molecule 2 0.97 0.575 0.769
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
NOX1 Q9Y5S8 NADPH oxidase 1 8.7E-08 0.536 0.808