Disease: Hereditary Diffuse Gastric Cancer
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ALOX5 P09917 arachidonate 5-lipoxygenase Enzyme 1.2E-06 0.447 0.885
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
APOA1 P02647 apolipoprotein A1 5.5E-04 0.429 0.885
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846
BIRC5 O15392 baculoviral IAP repeat containing 5 Enzyme modulator 5.6E-02 0.495 0.731
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CA1 P00915 carbonic anhydrase 1 4.7E-11 0.623 0.769
CA2 P00918 carbonic anhydrase 2 1.7E-06 0.506 0.808
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CDX2 Q99626 caudal type homeobox 2 Transcription factor 0.53 0.458 0.769
CKB P12277 creatine kinase B Kinase 0.22 0.608 0.615
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
CYP2A6 P11509 cytochrome P450 family 2 subfamily A member 6 5.4E-09 0.556 0.731
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ENO1 P06733 enolase 1 Enzyme 1.9E-05 0.481 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
FAT4 Q6V0I7 FAT atypical cadherin 4 1.00 0.539 0.808
GAST P01350 gastrin 2.7E-03 0.485 0.808
GKN1 Q9NS71 gastrokine 1 1.1E-06 0.628 0.615
GMPR2 Q9P2T1 guanosine monophosphate reductase 2 1.0E-08 0.769 0.115