Disease: Melanotic medulloblastoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SMYD4 Q8IYR2 SET and MYND domain containing 4 8.8E-15 0.792 0.077
SCML2 Q9UQR0 Scm polycomb group protein like 2 Nucleic acid binding 1.00 0.805 0.115
L3MBTL2 Q969R5 L3MBTL histone methyl-lysine binding protein 2 Nucleic acid binding 1.0E-08 0.729 0.308
L3MBTL3 Q96JM7 L3MBTL histone methyl-lysine binding protein 3 Epigenetic regulator 1.00 0.700 0.423
SCG5 P05408 secretogranin V Signaling 6.3E-05 0.663 0.462
KDM4B O94953 lysine demethylase 4B Epigenetic regulator 1.00 0.606 0.462
STRADA Q7RTN6 STE20 related adaptor alpha Kinase 4.5E-06 0.711 0.462
ATOH1 Q92858 atonal bHLH transcription factor 1 Enzyme 1.8E-02 0.633 0.500
BRD3 Q15059 bromodomain containing 3 Epigenetic regulator 0.97 0.700 0.500
PRAME P78395 preferentially expressed antigen in melanoma 2.4E-07 0.531 0.577
HIC1 Q14526 HIC ZBTB transcriptional repressor 1 Transcription factor 0.13 0.522 0.615
KDM4C Q9H3R0 lysine demethylase 4C 6.5E-07 0.601 0.615
IRS2 Q9Y4H2 insulin receptor substrate 2 0.99 0.535 0.654
FLI1 Q01543 Fli-1 proto-oncogene, ETS transcription factor Transcription factor 0.99 0.468 0.692
MPL P40238 MPL proto-oncogene, thrombopoietin receptor Receptor 4.1E-09 0.510 0.692
PTCH2 Q9Y6C5 patched 2 3.4E-16 0.563 0.692
CCNE1 P24864 cyclin E1 Enzyme modulator 0.97 0.538 0.731
CDK6 Q00534 cyclin dependent kinase 6 Kinase 0.98 0.471 0.731
MYCL P12524 MYCL proto-oncogene, bHLH transcription factor Transcription factor 0.12 0.599 0.731
S100A4 P26447 S100 calcium binding protein A4 Calcium-binding protein 6.2E-03 0.448 0.769
S100A10 P60903 S100 calcium binding protein A10 Calcium-binding protein 0.17 0.528 0.769
VAV1 P15498 vav guanine nucleotide exchange factor 1 1.00 0.556 0.769
KAT6A Q92794 lysine acetyltransferase 6A Enzyme 1.00 0.560 0.769
SUFU Q9UMX1 SUFU negative regulator of hedgehog signaling 1.00 0.493 0.769
MYCN P04198 MYCN proto-oncogene, bHLH transcription factor Transcription factor 0.89 0.454 0.808