Disease: Adrenal Cushing's syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CYP2B6 P20813 cytochrome P450 family 2 subfamily B member 6 1.9E-10 0.428 0.846
CYP11B1 P15538 cytochrome P450 family 11 subfamily B member 1 8.2E-07 0.563 0.615
CYP11B2 P19099 cytochrome P450 family 11 subfamily B member 2 7.1E-19 0.553 0.615
CYP17A1 P05093 cytochrome P450 family 17 subfamily A member 1 2.6E-04 0.462 0.769
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
LEP P41159 leptin 0.46 0.349 0.846
MEN1 O00255 menin 1 1.00 0.444 0.808
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846
STAR P49675 steroidogenic acute regulatory protein 8.8E-11 0.513 0.808
SULT2A1 Q06520 sulfotransferase family 2A member 1 1.3E-15 0.545 0.769
UTS2 O95399 urotensin 2 3.2E-02 0.564 0.808
PDE11A Q9HCR9 phosphodiesterase 11A 8.7E-37 0.612 0.654
ARMC5 Q96C12 armadillo repeat containing 5 0.11 0.670 0.500
ACAT1 P24752 acetyl-CoA acetyltransferase 1 Enzyme 9.9E-08 0.538 0.692
AKR1B1 P15121 aldo-keto reductase family 1 member B Enzyme 2.0E-05 0.491 0.885
FH P07954 fumarate hydratase Enzyme 8.8E-02 0.489 0.846
FOLH1 Q04609 folate hydrolase 1 Enzyme 6.2E-09 0.453 0.885
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
PMPCA Q10713 peptidase, mitochondrial processing subunit alpha Enzyme 3.4E-11 0.633 0.577
SERPINA3 P01011 serpin family A member 3 Enzyme modulator 8.8E-14 0.486 0.846
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846