Disease: Cushing Syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MEN1 O00255 menin 1 1.00 0.444 0.808
UTS2 O95399 urotensin 2 3.2E-02 0.564 0.808
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
SERPINA3 P01011 serpin family A member 3 Enzyme modulator 8.8E-14 0.486 0.846
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
CYP17A1 P05093 cytochrome P450 family 17 subfamily A member 1 2.6E-04 0.462 0.769
FH P07954 fumarate hydratase Enzyme 8.8E-02 0.489 0.846
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846
KRT5 P13647 keratin 5 0.64 0.512 0.731
CPA1 P15085 carboxypeptidase A1 Enzyme 2.7E-11 0.650 0.577
AKR1B1 P15121 aldo-keto reductase family 1 member B Enzyme 2.0E-05 0.491 0.885
CYP11B1 P15538 cytochrome P450 family 11 subfamily B member 1 8.2E-07 0.563 0.615
PRKACA P17612 protein kinase cAMP-activated catalytic subunit alpha Kinase 0.97 0.606 0.692
CYP11B2 P19099 cytochrome P450 family 11 subfamily B member 2 7.1E-19 0.553 0.615
LHCGR P22888 luteinizing hormone/choriogonadotropin receptor G-protein coupled receptor 5.3E-08 0.528 0.692
ACAT1 P24752 acetyl-CoA acetyltransferase 1 Enzyme 9.9E-08 0.538 0.692
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885