Disease: Tuberous Sclerosis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923
IL23A Q9NPF7 interleukin 23 subunit alpha Signaling 0.36 0.415 0.846
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
S100A1 P23297 S100 calcium binding protein A1 Calcium-binding protein 6.0E-03 0.421 0.846
STK11 Q15831 serine/threonine kinase 11 Kinase 0.99 0.435 0.808
TSC2 P49815 TSC complex subunit 2 Enzyme modulator 1.00 0.439 0.808
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
TSC1 Q92574 TSC complex subunit 1 1.00 0.440 0.808
ANXA1 P04083 annexin A1 1.2E-07 0.442 0.885
SGSM3 Q96HU1 small G protein signaling modulator 3 Enzyme 3.4E-15 0.469 0.808
C20orf181 chromosome 20 open reading frame 181 0.479 0.885