Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
LMNA | P02545 | lamin A/C | 1.00 | 0.384 | 0.885 | |
PTPN11 | Q06124 | protein tyrosine phosphatase non-receptor type 11 | 1.00 | 0.385 | 0.923 | |
HRAS | P01112 | HRas proto-oncogene, GTPase | Enzyme modulator | 8.0E-02 | 0.378 | 0.885 |
NRAS | P01111 | NRAS proto-oncogene, GTPase | Enzyme modulator | 0.49 | 0.390 | 0.808 |
IGF1R | P08069 | insulin like growth factor 1 receptor | Kinase | 0.97 | 0.399 | 0.885 |
KMT2A | Q03164 | lysine methyltransferase 2A | 1.00 | 0.410 | 0.885 | |
RAF1 | P04049 | Raf-1 proto-oncogene, serine/threonine kinase | Kinase | 0.85 | 0.418 | 0.885 |
CHD7 | Q9P2D1 | chromodomain helicase DNA binding protein 7 | 1.00 | 0.441 | 0.846 | |
MAP2K1 | Q02750 | mitogen-activated protein kinase kinase 1 | Kinase | 0.90 | 0.439 | 0.846 |
NF1 | P21359 | neurofibromin 1 | Enzyme modulator | 0.90 | 0.440 | 0.885 |
TTN | Q8WZ42 | titin | Kinase | 2.6E-96 | 0.470 | 0.885 |
RB1 | P06400 | RB transcriptional corepressor 1 | Nucleic acid binding | 1.00 | 0.444 | 0.885 |
CDC42 | P60953 | cell division cycle 42 | Enzyme modulator | 0.79 | 0.458 | 0.846 |
NKX2-1 | P43699 | NK2 homeobox 1 | Transcription factor | 0.36 | 0.457 | 0.808 |
FLI1 | Q01543 | Fli-1 proto-oncogene, ETS transcription factor | Transcription factor | 0.99 | 0.468 | 0.692 |
SRY | Q05066 | sex determining region Y | Transcription factor | 0.456 | 0.808 | |
BCOR | Q6W2J9 | BCL6 corepressor | 1.00 | 0.471 | 0.808 | |
GPC3 | P51654 | glypican 3 | 1.00 | 0.466 | 0.808 | |
ACTG1 | P63261 | actin gamma 1 | Cellular structure | 4.8E-03 | 0.477 | 0.846 |
ZMPSTE24 | O75844 | zinc metallopeptidase STE24 | Enzyme | 8.9E-16 | 0.517 | 0.731 |
SMS | P52788 | spermine synthase | 0.97 | 0.491 | 0.846 |