Disease: Midface retrusion
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
LMNA P02545 lamin A/C 1.00 0.384 0.885
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
TWIST1 Q15672 twist family bHLH transcription factor 1 Transcription factor 0.34 0.397 0.846
PTCH1 Q13635 patched 1 1.00 0.398 0.885
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
FLNA P21333 filamin A 1.00 0.419 0.846
BMP4 P12644 bone morphogenetic protein 4 Signaling 0.96 0.422 0.808
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846
RUNX2 Q13950 RUNX family transcription factor 2 Transcription factor 0.95 0.437 0.846
WNT5A P41221 Wnt family member 5A Signaling 0.99 0.443 0.808
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808
FLNB O75369 filamin B 6.1E-10 0.458 0.923
EHMT1 Q9H9B1 euchromatic histone lysine methyltransferase 1 Epigenetic regulator 1.00 0.460 0.808