Disease: Peripheral axonal neuropathy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AARS1 P49588 alanyl-tRNA synthetase 1 Nucleic acid binding 1.8E-08 0.647 0.462
ASCC1 Q8N9N2 activating signal cointegrator 1 complex subunit 1 2.6E-14 0.495 0.846
BIN1 O00499 bridging integrator 1 0.78 0.550 0.692
C12orf65 Q9H3J6 chromosome 12 open reading frame 65 Nucleic acid binding 0.21 0.678 0.346
DCAF8 Q5TAQ9 DDB1 and CUL4 associated factor 8 Enzyme modulator 1.00 0.821 0.115
DNM2 P50570 dynamin 2 Enzyme modulator 1.00 0.542 0.769
GDAP1 Q8TB36 ganglioside induced differentiation associated protein 1 3.2E-08 0.612 0.538
HADHB P55084 hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta Enzyme 1.5E-11 0.619 0.692
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
HSPB8 Q9UJY1 heat shock protein family B (small) member 8 4.3E-02 0.570 0.577
IBA57 Q5T440 iron-sulfur cluster assembly factor IBA57 8.4E-03 0.666 0.423
IFRD1 O00458 interferon related developmental regulator 1 1.2E-03 0.666 0.462
KIF1A Q12756 kinesin family member 1A Cellular structure 1.00 0.559 0.692
KIF1B O60333 kinesin family member 1B Cellular structure 1.00 0.516 0.808
LMNA P02545 lamin A/C 1.00 0.384 0.885
MARS1 P56192 methionyl-tRNA synthetase 1 2.1E-15 0.638 0.654
MCM3AP O60318 minichromosome maintenance complex component 3 associated protein 5.2E-09 0.647 0.654
MED25 Q71SY5 mediator complex subunit 25 Transcription factor 8.4E-07 0.582 0.654
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
MPV17 P39210 mitochondrial inner membrane protein MPV17 Receptor 9.7E-11 0.595 0.577
MPZ P25189 myelin protein zero 0.27 0.503 0.846
MTMR14 Q8NCE2 myotubularin related protein 14 1.4E-07 0.674 0.615
NEFL P07196 neurofilament light 0.488 0.769
OPA1 O60313 OPA1 mitochondrial dynamin like GTPase Enzyme modulator 0.99 0.510 0.846