Disease: Charcot-Marie-Tooth Disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AARS1 P49588 alanyl-tRNA synthetase 1 Nucleic acid binding 1.8E-08 0.647 0.462
AARS2 Q5JTZ9 alanyl-tRNA synthetase 2, mitochondrial Nucleic acid binding 5.0E-17 0.644 0.500
AIFM1 O95831 apoptosis inducing factor mitochondria associated 1 Enzyme 1.00 0.527 0.769
ATP7A Q04656 ATPase copper transporting alpha Transporter 1.00 0.494 0.769
BSCL2 Q96G97 BSCL2 lipid droplet biogenesis associated, seipin 1.1E-09 0.545 0.692
CMTX3 Charcot-Marie-Tooth neuropathy, X-linked 3 (dominant) 0.821 0.154
DNAJB2 P25686 DnaJ heat shock protein family (Hsp40) member B2 5.4E-05 0.743 0.192
GAN Q9H2C0 gigaxonin 2.5E-02 0.674 0.500
GARS1 P41250 glycyl-tRNA synthetase 1 Enzyme 0.31 0.623 0.500
GART P22102 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase Enzyme 2.8E-04 0.631 0.615
HINT1 P49773 histidine triad nucleotide binding protein 1 Enzyme 1.8E-03 0.619 0.577
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
HSPB2 Q16082 heat shock protein family B (small) member 2 3.3E-04 0.457 0.769
HSPB3 Q12988 heat shock protein family B (small) member 3 6.1E-05 0.448 0.769
HSPB8 Q9UJY1 heat shock protein family B (small) member 8 4.3E-02 0.570 0.577
KIF1B O60333 kinesin family member 1B Cellular structure 1.00 0.516 0.808
MAD2L1BP Q15013 MAD2L1 binding protein 1.4E-08 0.623 0.577
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
MPZ P25189 myelin protein zero 0.27 0.503 0.846
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
RAB7A P51149 RAB7A, member RAS oncogene family 0.97 0.597 0.692
RAB7B Q96AH8 RAB7B, member RAS oncogene family 0.615 0.731
RNMT O43148 RNA guanine-7 methyltransferase 5.7E-05 0.647 0.500
SETX Q7Z333 senataxin Enzyme 0.95 0.570 0.731