Disease: Talipes cavus
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AARS1 P49588 alanyl-tRNA synthetase 1 Nucleic acid binding 1.8E-08 0.647 0.462
AIFM1 O95831 apoptosis inducing factor mitochondria associated 1 Enzyme 1.00 0.527 0.769
APTX Q7Z2E3 aprataxin Nucleic acid binding 4.0E-10 0.590 0.500
ATL1 Q8WXF7 atlastin GTPase 1 Enzyme modulator 0.98 0.593 0.654
ATP7A Q04656 ATPase copper transporting alpha Transporter 1.00 0.494 0.769
BSCL2 Q96G97 BSCL2 lipid droplet biogenesis associated, seipin 1.1E-09 0.545 0.692
CHCHD10 Q8WYQ3 coiled-coil-helix-coiled-coil-helix domain containing 10 5.4E-06 0.623 0.462
GAN Q9H2C0 gigaxonin 2.5E-02 0.674 0.500
GARS1 P41250 glycyl-tRNA synthetase 1 Enzyme 0.31 0.623 0.500
HINT1 P49773 histidine triad nucleotide binding protein 1 Enzyme 1.8E-03 0.619 0.577
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
HSPB8 Q9UJY1 heat shock protein family B (small) member 8 4.3E-02 0.570 0.577
KIF1B O60333 kinesin family member 1B Cellular structure 1.00 0.516 0.808
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
MPZ P25189 myelin protein zero 0.27 0.503 0.846
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
RAB7A P51149 RAB7A, member RAS oncogene family 0.97 0.597 0.692
REEP1 Q9H902 receptor accessory protein 1 Transporter 0.99 0.653 0.423
SETX Q7Z333 senataxin Enzyme 0.95 0.570 0.731
SIGMAR1 Q99720 sigma non-opioid intracellular receptor 1 0.17 0.544 0.808
SYT2 Q8N9I0 synaptotagmin 2 Transporter 0.98 0.647 0.538
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808
VCP P55072 valosin containing protein 1.00 0.469 0.923
WARS1 P23381 tryptophanyl-tRNA synthetase 1 Enzyme 0.30 0.650 0.654