Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
ADRB2 P07550 adrenoceptor beta 2 G-protein coupled receptor 0.53 0.442 0.923
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
ATP7A Q04656 ATPase copper transporting alpha Transporter 1.00 0.494 0.769
SCN8A Q9UQD0 sodium voltage-gated channel alpha subunit 8 Ion channel 1.00 0.510 0.731
SCN2A Q99250 sodium voltage-gated channel alpha subunit 2 Ion channel 1.00 0.518 0.731
TRH P20396 thyrotropin releasing hormone 8.9E-04 0.519 0.846
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846
ADORA2A P29274 adenosine A2a receptor G-protein coupled receptor 0.60 0.526 0.769
RPGRIP1L Q68CZ1 RPGRIP1 like Enzyme modulator 4.1E-31 0.534 0.769
UBE3A Q05086 ubiquitin protein ligase E3A 1.00 0.561 0.692
SLC12A6 Q9UHW9 solute carrier family 12 member 6 Transporter 1.1E-02 0.603 0.500
MS multiple sclerosis 0.599 0.692
PPP2R2B Q00005 protein phosphatase 2 regulatory subunit Bbeta Enzyme 0.98 0.601 0.577
CIZ1 Q9ULV3 CDKN1A interacting zinc finger protein 1 6.3E-02 0.617 0.500
ITPA Q9BY32 inosine triphosphatase Enzyme 1.0E-07 0.604 0.500
PGAP1 Q75T13 post-GPI attachment to proteins inositol deacylase 1 Transporter 3.2E-08 0.650 0.423
EARS2 Q5JPH6 glutamyl-tRNA synthetase 2, mitochondrial Enzyme 1.1E-08 0.666 0.538
CHRM4 P08173 cholinergic receptor muscarinic 4 G-protein coupled receptor 0.97 0.821 0.231