Disease: Pulmonary arterial hypertension
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACTA2 P62736 actin alpha 2, smooth muscle Cellular structure 0.93 0.508 0.846
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846
ANGPT1 Q15389 angiopoietin 1 Signaling 0.95 0.446 0.808
AXIN2 Q9Y2T1 axin 2 0.57 0.507 0.692
BMPR2 Q13873 bone morphogenetic protein receptor type 2 Kinase 1.00 0.538 0.654
CASR P41180 calcium sensing receptor G-protein coupled receptor 4.7E-02 0.410 0.846
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846
CHDH Q8NE62 choline dehydrogenase Enzyme 1.7E-06 0.529 0.769
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
EDNRA P25101 endothelin receptor type A G-protein coupled receptor 0.99 0.426 0.885
ENG P17813 endoglin 1.00 0.446 0.846
EPAS1 Q99814 endothelial PAS domain protein 1 Transcription factor 0.60 0.454 0.731
ERN1 O75460 endoplasmic reticulum to nucleus signaling 1 Kinase 0.99 0.513 0.808
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
FGF7 P21781 fibroblast growth factor 7 Signaling 0.77 0.519 0.846
FLNA P21333 filamin A 1.00 0.419 0.846
FOXF1 Q12946 forkhead box F1 0.96 0.540 0.692
GATA6 Q92908 GATA binding protein 6 1.00 0.478 0.808
GJB2 P29033 gap junction protein beta 2 Cell-cell junction 6.6E-16 0.441 0.846