Disease: 2-3 toe syndactyly
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
ACSL4 O60488 acyl-CoA synthetase long chain family member 4 Enzyme 0.98 0.561 0.769
AGTR2 P50052 angiotensin II receptor type 2 G-protein coupled receptor 8.2E-03 0.496 0.808
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
CDC45 O75419 cell division cycle 45 Nucleic acid binding 4.6E-05 0.588 0.692
CEP55 Q53EZ4 centrosomal protein 55 2.0E-12 0.534 0.731
DMD P11532 dystrophin 1.00 0.423 0.923
EBP Q15125 EBP cholestenol delta-isomerase Enzyme 0.94 0.494 0.846
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
HOXD13 P35453 homeobox D13 8.6E-03 0.483 0.808
HUWE1 Q7Z6Z7 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 Enzyme 1.00 0.534 0.769
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769
MYCN P04198 MYCN proto-oncogene, bHLH transcription factor Transcription factor 0.89 0.454 0.808
NEDD4L Q96PU5 NEDD4 like E3 ubiquitin protein ligase Enzyme 1.00 0.573 0.731
NIPBL Q6KC79 NIPBL cohesin loading factor Nucleic acid binding 1.00 0.521 0.808
NOG Q13253 noggin 0.89 0.518 0.731
PTCH1 Q13635 patched 1 1.00 0.398 0.885
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846
RHOBTB2 Q9BYZ6 Rho related BTB domain containing 2 Enzyme modulator 1.3E-02 0.631 0.615
RPS6KA3 P51812 ribosomal protein S6 kinase A3 Kinase 1.00 0.491 0.846
SIK3 Q9Y2K2 SIK family kinase 3 Kinase 1.00 0.631 0.654
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
SOX5 P35711 SRY-box transcription factor 5 1.00 0.545 0.769