Disease: Frontotemporal Lobar Degeneration
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKR1C4 P17516 aldo-keto reductase family 1 member C4 Enzyme 2.2E-17 0.587 0.846
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CDR1 P51861 cerebellar degeneration related protein 1 0.576 0.808
CHMP2B Q9UQN3 charged multivesicular body protein 2B 4.6E-06 0.543 0.731
CP P00450 ceruloplasmin Enzyme 4.2E-10 0.466 0.846
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
GFRA2 O00451 GDNF family receptor alpha 2 9.8E-02 0.716 0.423
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
HCRT O43612 hypocretin neuropeptide precursor 2.9E-02 0.500 0.808
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
HTT P42858 huntingtin 1.00 0.548 0.654
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
IL6 P05231 interleukin 6 0.32 0.248 0.962
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
LEP P41159 leptin 0.46 0.349 0.846
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808