Disease: Cancer cachexia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
GRAP2 O75791 GRB2 related adaptor protein 2 1.5E-04 0.394 0.923
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
PNPLA2 Q96AD5 patatin like phospholipase domain containing 2 Enzyme 4.1E-03 0.511 0.846
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
AIMP2 Q13155 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 8.0E-03 0.393 0.923
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923
XBP1 P17861 X-box binding protein 1 3.2E-02 0.477 0.846
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
MYD88 Q99836 MYD88 innate immune signal transduction adaptor Enzyme modulator 0.12 0.414 0.923
PAX7 P23759 paired box 7 0.14 0.597 0.538
IL6 P05231 interleukin 6 0.32 0.248 0.962
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
POLDIP2 Q9Y2S7 DNA polymerase delta interacting protein 2 0.41 0.396 0.923
IFNG P01579 interferon gamma 0.47 0.288 0.962
MSTN O14793 myostatin Signaling 0.51 0.528 0.731
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
IL15 P40933 interleukin 15 0.71 0.422 0.846
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
CRK P46108 CRK proto-oncogene, adaptor protein 0.96 0.394 0.923
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923