Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
RBBP8 Q99708 RB binding protein 8, endonuclease Transcription factor 3.1E-12 0.584 0.808
CEP152 O94986 centrosomal protein 152 Signaling 2.7E-27 0.653 0.500
H2AX P16104 H2A.X variant histone Nucleic acid binding 0.18 0.484 0.808
MCPH1 Q8NEM0 microcephalin 1 Nucleic acid binding 7.8E-30 0.540 0.846
ORC1 Q13415 origin recognition complex subunit 1 Nucleic acid binding 1.7E-14 0.595 0.654
ORC6 Q9Y5N6 origin recognition complex subunit 6 Nucleic acid binding 3.4E-07 0.628 0.577
ORC4 O43929 origin recognition complex subunit 4 Nucleic acid binding 7.6E-13 0.612 0.654
WDR4 P57081 WD repeat domain 4 Nucleic acid binding 1.4E-08 0.653 0.538
LARP7 Q4G0J3 La ribonucleoprotein 7, transcriptional regulator Nucleic acid binding 9.3E-08 0.674 0.615
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923
CHEK1 O14757 checkpoint kinase 1 Kinase 3.1E-08 0.492 0.808
PLK4 O00444 polo like kinase 4 Kinase 7.1E-06 0.551 0.731
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
SOS1 Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 1.00 0.485 0.808
RIT1 Q92963 Ras like without CAAX 1 Enzyme modulator 0.13 0.527 0.808
CEP135 Q66GS9 centrosomal protein 135 Enzyme modulator 3.6E-22 0.695 0.615
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923
CENPJ Q9HC77 centromere protein J Enzyme 2.1E-27 0.546 0.846
CD5L O43866 CD5 molecule like Enzyme 4.2E-17 0.593 0.846