Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
AIMP2 Q13155 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 8.0E-03 0.393 0.923
CRK P46108 CRK proto-oncogene, adaptor protein 0.96 0.394 0.923
GRAP2 O75791 GRB2 related adaptor protein 2 1.5E-04 0.394 0.923
POLDIP2 Q9Y2S7 DNA polymerase delta interacting protein 2 0.41 0.396 0.923
AHSA1 O95433 activator of HSP90 ATPase activity 1 1.00 0.396 0.923
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923
LIG4 P49917 DNA ligase 4 4.2E-06 0.478 0.846
SOS1 Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 1.00 0.485 0.808
FANCC Q00597 FA complementation group C 2.8E-13 0.507 0.808
H2AX P16104 H2A.X variant histone Nucleic acid binding 0.18 0.484 0.808
FANCA O15360 FA complementation group A 1.6E-68 0.505 0.731
CD69 Q07108 CD69 molecule 3.0E-02 0.488 0.923
CHEK1 O14757 checkpoint kinase 1 Kinase 3.1E-08 0.492 0.808
XRCC4 Q13426 X-ray repair cross complementing 4 8.3E-07 0.528 0.769