Disease: Holoprosencephaly
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BUB1 O43683 BUB1 mitotic checkpoint serine/threonine kinase Kinase 4.9E-09 0.528 0.731
BUB1B O60566 BUB1 mitotic checkpoint serine/threonine kinase B Kinase 7.0E-10 0.502 0.808
BUB3 O43684 BUB3 mitotic checkpoint protein Nucleic acid binding 0.81 0.588 0.615
CDON Q4KMG0 cell adhesion associated, oncogene regulated 2.1E-15 0.601 0.731
CEP57 Q86XR8 centrosomal protein 57 7.3E-02 0.615 0.615
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846
DISP1 Q96F81 dispatched RND transporter family member 1 8.9E-08 0.644 0.692
DLL1 O00548 delta like canonical Notch ligand 1 1.00 0.492 0.808
FGF8 P55075 fibroblast growth factor 8 Signaling 0.68 0.507 0.769
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
FOXH1 O75593 forkhead box H1 4.2E-02 0.615 0.654
GAS1 P54826 growth arrest specific 1 0.82 0.587 0.654
GLI2 P10070 GLI family zinc finger 2 0.97 0.446 0.846
NODAL Q96S42 nodal growth differentiation factor Signaling 0.97 0.588 0.731
PIGN O95427 phosphatidylinositol glycan anchor biosynthesis class N Extracellular structure 2.3E-21 0.558 0.615
PTCH1 Q13635 patched 1 1.00 0.398 0.885
SEMA3E O15041 semaphorin 3E Signaling 8.7E-09 0.515 0.769
SHH Q15465 sonic hedgehog signaling molecule 0.98 0.461 0.846
SIX3 O95343 SIX homeobox 3 Transcription factor 0.95 0.560 0.692
SUFU Q9UMX1 SUFU negative regulator of hedgehog signaling 1.00 0.493 0.769
TDGF1 P13385 teratocarcinoma-derived growth factor 1 Calcium-binding protein 9.2E-11 0.584 0.731
TGIF1 Q15583 TGFB induced factor homeobox 1 Enzyme 1.0E-02 0.588 0.769
TRIP13 Q15645 thyroid hormone receptor interactor 13 1.00 0.559 0.654
ZIC2 O95409 Zic family member 2 Transcription factor 0.97 0.556 0.769