Disease: Progressive supranuclear palsy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
ATXN8OS P0DMR3 ATXN8 opposite strand lncRNA 0.650 0.423
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CIT O14578 citron rho-interacting serine/threonine kinase Kinase 1.00 0.555 0.692
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
PAFAH1B1 P43034 platelet activating factor acetylhydrolase 1b regulatory subunit 1 1.00 0.504 0.769
PICALM Q13492 phosphatidylinositol binding clathrin assembly protein Transporter 1.00 0.592 0.538
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
YWHAE P62258 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon Chaperone 0.98 0.530 0.692