Disease: Mild cognitive disorder
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
BIN1 O00499 bridging integrator 1 0.78 0.550 0.692
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846
UBE2I P63279 ubiquitin conjugating enzyme E2 I 0.96 0.544 0.769
NECTIN2 Q92692 nectin cell adhesion molecule 2 0.97 0.575 0.769
RAB7A P51149 RAB7A, member RAS oncogene family 0.97 0.597 0.692
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
CYP46A1 Q9Y6A2 cytochrome P450 family 46 subfamily A member 1 Enzyme 0.99 0.659 0.500
TOMM40 O96008 translocase of outer mitochondrial membrane 40 Transporter 0.99 0.590 0.538
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
UBQLN1 Q9UMX0 ubiquilin 1 1.00 0.650 0.423
PICALM Q13492 phosphatidylinositol binding clathrin assembly protein Transporter 1.00 0.592 0.538
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
LRP8 Q14114 LDL receptor related protein 8 1.00 0.644 0.346
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
ADAM10 O14672 ADAM metallopeptidase domain 10 1.00 0.489 0.846