Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
MMP9 | P14780 | matrix metallopeptidase 9 | Enzyme | 1.9E-17 | 0.305 | 0.923 |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
CCND1 | P24385 | cyclin D1 | Enzyme modulator | 0.89 | 0.344 | 0.923 |
LMNA | P02545 | lamin A/C | 1.00 | 0.384 | 0.885 | |
TP63 | Q9H3D4 | tumor protein p63 | Transcription factor | 1.00 | 0.362 | 0.769 |
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
FGFR2 | P21802 | fibroblast growth factor receptor 2 | Kinase | 1.00 | 0.380 | 0.808 |
RET | P07949 | ret proto-oncogene | Kinase | 1.00 | 0.392 | 0.885 |
TWIST1 | Q15672 | twist family bHLH transcription factor 1 | Transcription factor | 0.34 | 0.397 | 0.846 |
MLH1 | P40692 | mutL homolog 1 | Nucleic acid binding | 3.4E-05 | 0.399 | 0.808 |
CDH1 | P12830 | cadherin 1 | 0.15 | 0.401 | 0.808 | |
MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
RPE65 | Q16518 | retinoid isomerohydrolase RPE65 | Enzyme | 6.5E-14 | 0.417 | 0.808 |
PGR | P06401 | progesterone receptor | Nuclear receptor | 5.1E-02 | 0.426 | 0.885 |
UVRAG | Q9P2Y5 | UV radiation resistance associated | 0.99 | 0.436 | 0.769 | |
CKAP4 | Q07065 | cytoskeleton associated protein 4 | 0.51 | 0.436 | 0.731 | |
KHDRBS1 | Q07666 | KH RNA binding domain containing, signal transduction associated 1 | Nucleic acid binding | 0.99 | 0.457 | 0.846 |
MIR375 | microRNA 375 | 0.476 | 0.769 | |||
LGR6 | Q9HBX8 | leucine rich repeat containing G protein-coupled receptor 6 | G-protein coupled receptor | 2.9E-06 | 0.502 | 0.923 |
CLDN7 | O95471 | claudin 7 | Cell-cell junction | 2.9E-03 | 0.494 | 0.808 |
CTCF | P49711 | CCCTC-binding factor | Transcription factor | 1.00 | 0.504 | 0.769 |