Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CYP46A1 Q9Y6A2 cytochrome P450 family 46 subfamily A member 1 Enzyme 0.99 0.659 0.500
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
TMEM106B Q9NUM4 transmembrane protein 106B 0.33 0.590 0.462
ABCB6 Q9NP58 ATP binding cassette subfamily B member 6 (Langereis blood group) Transporter 8.6E-19 0.431 0.885
SLC30A3 Q99726 solute carrier family 30 member 3 Transporter 0.54 0.691 0.423
P2RX7 Q99572 purinergic receptor P2X 7 Ion channel 3.3E-11 0.450 0.808
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808
CETN1 Q12798 centrin 1 Calcium-binding protein 0.22 0.584 0.654
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
AQP4 P55087 aquaporin 4 Ion channel 2.3E-03 0.456 0.885
TRPC1 P48995 transient receptor potential cation channel subfamily C member 1 Ion channel 1.3E-02 0.566 0.769
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
GLP1R P43220 glucagon like peptide 1 receptor G-protein coupled receptor 0.29 0.471 0.846
HTT P42858 huntingtin 1.00 0.548 0.654
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962