Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
CCND1 | P24385 | cyclin D1 | Enzyme modulator | 0.89 | 0.344 | 0.923 |
FGFR1 | P11362 | fibroblast growth factor receptor 1 | Kinase | 1.00 | 0.362 | 0.885 |
FGFR2 | P21802 | fibroblast growth factor receptor 2 | Kinase | 1.00 | 0.380 | 0.808 |
APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 | |
PRKAR1A | P10644 | protein kinase cAMP-dependent type I regulatory subunit alpha | 1.00 | 0.401 | 0.846 | |
HSPA4 | P34932 | heat shock protein family A (Hsp70) member 4 | 1.00 | 0.394 | 0.923 | |
CYP19A1 | P11511 | cytochrome P450 family 19 subfamily A member 1 | Enzyme | 1.7E-05 | 0.410 | 0.885 |
CDH1 | P12830 | cadherin 1 | 0.15 | 0.401 | 0.808 | |
PDCD1 | Q15116 | programmed cell death 1 | 0.42 | 0.402 | 0.846 | |
CD68 | P34810 | CD68 molecule | Transporter | 1.4E-06 | 0.408 | 0.808 |
RASSF1 | Q9NS23 | Ras association domain family member 1 | Enzyme modulator | 4.9E-06 | 0.420 | 0.808 |
APRT | P07741 | adenine phosphoribosyltransferase | 5.5E-13 | 0.423 | 0.846 | |
YAP1 | P46937 | Yes associated protein 1 | Enzyme modulator | 1.00 | 0.432 | 0.808 |
PRKCA | P17252 | protein kinase C alpha | Kinase | 0.37 | 0.440 | 0.846 |
MFAP1 | P55081 | microfibril associated protein 1 | Extracellular structure | 0.80 | 0.431 | 0.846 |
SDC1 | P18827 | syndecan 1 | Extracellular structure | 8.4E-03 | 0.445 | 0.769 |
BRD2 | P25440 | bromodomain containing 2 | Epigenetic regulator | 1.00 | 0.450 | 0.808 |
HNF1A | P20823 | HNF1 homeobox A | Nucleic acid binding | 0.96 | 0.478 | 0.846 |
KRT19 | P08727 | keratin 19 | 4.3E-03 | 0.460 | 0.731 |