Disease: Congenital Abnormality
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
BRD2 P25440 bromodomain containing 2 Epigenetic regulator 1.00 0.450 0.808
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
JAG1 P78504 jagged canonical Notch ligand 1 1.00 0.429 0.808
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
TP53BP1 Q12888 tumor protein p53 binding protein 1 Epigenetic regulator 1.00 0.520 0.731