Disease: Pituitary-dependent Cushing's disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AIP O00170 aryl hydrocarbon receptor interacting protein Chaperone 0.36 0.517 0.769
BRD2 P25440 bromodomain containing 2 Epigenetic regulator 1.00 0.450 0.808
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
GNAI2 P04899 G protein subunit alpha i2 Enzyme modulator 0.89 0.636 0.577
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
H3P10 H3 histone pseudogene 10 0.350 0.846
HSD11B1 P28845 hydroxysteroid 11-beta dehydrogenase 1 0.42 0.520 0.731
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
MEN1 O00255 menin 1 1.00 0.444 0.808
NR2C2 P49116 nuclear receptor subfamily 2 group C member 2 Nuclear receptor 1.00 0.534 0.808
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885
SST P61278 somatostatin Signaling 0.34 0.399 0.885
SSTR1 P30872 somatostatin receptor 1 G-protein coupled receptor 0.75 0.606 0.615
SSTR2 P30874 somatostatin receptor 2 G-protein coupled receptor 0.44 0.539 0.731
SSTR5 P35346 somatostatin receptor 5 G-protein coupled receptor 9.6E-04 0.590 0.615
TBX19 O60806 T-box transcription factor 19 Transcription factor 7.1E-06 0.695 0.462
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962