Disease: MAJOR AFFECTIVE DISORDER 1
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ADRB2 P07550 adrenoceptor beta 2 G-protein coupled receptor 0.53 0.442 0.923
ANK3 Q12955 ankyrin 3 1.00 0.578 0.654
ARNTL O00327 aryl hydrocarbon receptor nuclear translocator like Transcription factor 0.99 0.510 0.885
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
BFAR Q9NZS9 bifunctional apoptosis regulator 1.5E-08 0.663 0.654
CACNA1C Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 1.00 0.510 0.846
CLOCK O15516 clock circadian regulator 1.00 0.463 0.885
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
DAOA P59103 D-amino acid oxidase activator 1.4E-04 0.678 0.346
DISC1 Q9NRI5 DISC1 scaffold protein 1.7E-06 0.548 0.769
DLX4 Q92988 distal-less homeobox 4 Transcription factor 1.7E-02 0.585 0.654
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808
DRD5 P21918 dopamine receptor D5 G-protein coupled receptor 1.3E-16 0.603 0.423
DTNBP1 Q96EV8 dystrobrevin binding protein 1 6.8E-06 0.588 0.615
EIF4EBP1 Q13541 eukaryotic translation initiation factor 4E binding protein 1 Nucleic acid binding 0.21 0.494 0.885
GAD1 Q99259 glutamate decarboxylase 1 Enzyme 4.6E-02 0.486 0.885
GRK3 P35626 G protein-coupled receptor kinase 3 Kinase 0.71 0.621 0.731
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IGFBP2 P18065 insulin like growth factor binding protein 2 Enzyme modulator 0.12 0.478 0.769
MAFD2 major affective disorder 2 0.641 0.731
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
NR1H4 Q96RI1 nuclear receptor subfamily 1 group H member 4 Nuclear receptor 9.4E-04 0.513 0.808
NRG1 Q02297 neuregulin 1 Signaling 1.00 0.464 0.885