Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
MSH3 P20585 mutS homolog 3 Nucleic acid binding 7.4E-31 0.474 0.769
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
CHEK1 O14757 checkpoint kinase 1 Kinase 3.1E-08 0.492 0.808
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
RASSF1 Q9NS23 Ras association domain family member 1 Enzyme modulator 4.9E-06 0.420 0.808
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
MUTYH Q9UIF7 mutY DNA glycosylase Enzyme 1.3E-18 0.521 0.769
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
SOAT1 P35610 sterol O-acyltransferase 1 Enzyme 7.4E-10 0.424 0.846
WIF1 Q9Y5W5 WNT inhibitory factor 1 Calcium-binding protein 1.3E-09 0.507 0.731
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
BLM P54132 BLM RecQ like helicase 1.5E-15 0.535 0.808
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962