Disease: FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder)
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
FANCA O15360 FA complementation group A 1.6E-68 0.505 0.731
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
NLRP2 Q9NX02 NLR family pyrin domain containing 2 1.4E-38 0.515 0.731
FANCI Q9NVI1 FA complementation group I 8.9E-37 0.543 0.731
WRN Q14191 WRN RecQ like helicase Enzyme 2.6E-34 0.524 0.808
MSH3 P20585 mutS homolog 3 Nucleic acid binding 7.4E-31 0.474 0.769
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
RAD50 Q92878 RAD50 double strand break repair protein 3.4E-27 0.556 0.808
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
FANCL Q9NW38 FA complementation group L Enzyme 5.9E-23 0.551 0.731
SLX4 Q8IY92 SLX4 structure-specific endonuclease subunit 1.6E-22 0.565 0.731
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
BLM P54132 BLM RecQ like helicase 1.5E-15 0.535 0.808
RAD51B O15315 RAD51 paralog B 2.1E-15 0.556 0.769
FANCM Q8IYD8 FA complementation group M Enzyme 2.4E-15 0.543 0.731
RAD51C O43502 RAD51 paralog C 6.2E-14 0.533 0.692
EXO1 Q9UQ84 exonuclease 1 Enzyme 8.1E-13 0.578 0.692
MRE11 P49959 MRE11 homolog, double strand break repair nuclease 1.3E-12 0.527 0.808
ERCC4 Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 1.4E-12 0.468 0.846
PPM1D O15297 protein phosphatase, Mg2+/Mn2+ dependent 1D Enzyme 2.2E-11 0.513 0.808