Disease: Hereditary Breast and Ovarian Cancer Syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
RAD50 Q92878 RAD50 double strand break repair protein 3.4E-27 0.556 0.808
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846
RAD51B O15315 RAD51 paralog B 2.1E-15 0.556 0.769
RAD51C O43502 RAD51 paralog C 6.2E-14 0.533 0.692
RAD51D O75771 RAD51 paralog D 1.1E-09 0.674 0.385
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962