Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923
MAPK8 P45983 mitogen-activated protein kinase 8 Kinase 1.00 0.397 0.885
IFNA2 P01563 interferon alpha 2 0.442 0.885
PLXNA2 O75051 plexin A2 1.1E-06 0.447 0.808
BAP1 Q92560 BRCA1 associated protein 1 Enzyme 0.99 0.454 0.731
BAG3 O95817 BAG cochaperone 3 0.62 0.498 0.846
GNAQ P50148 G protein subunit alpha q Enzyme modulator 0.98 0.516 0.808
TYRP1 P17643 tyrosinase related protein 1 Enzyme 6.6E-25 0.507 0.846
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
DDR2 Q16832 discoidin domain receptor tyrosine kinase 2 Kinase 0.55 0.541 0.769
GNA11 P29992 G protein subunit alpha 11 Enzyme modulator 0.89 0.563 0.731
MARCKS P29966 myristoylated alanine rich protein kinase C substrate 0.33 0.559 0.769
CYSLTR2 Q9NS75 cysteinyl leukotriene receptor 2 G-protein coupled receptor 1.0E-04 0.633 0.538
PERP Q96FX8 p53 apoptosis effector related to PMP22 7.9E-02 0.663 0.577
HAT1 O14929 histone acetyltransferase 1 Enzyme 0.84 0.656 0.500
KYAT1 Q16773 kynurenine aminotransferase 1 Enzyme 1.9E-12 0.736 0.308