Disease: Hereditary Diffuse Gastric Cancer
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
FHIT P49789 fragile histidine triad diadenosine triphosphatase 5.7E-03 0.444 0.846
GADD45A P24522 growth arrest and DNA damage inducible alpha 4.4E-02 0.526 0.769
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
IGFBP3 P17936 insulin like growth factor binding protein 3 Enzyme modulator 0.91 0.439 0.808
IGFBP7 Q16270 insulin like growth factor binding protein 7 1.3E-03 0.476 0.769
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923
IL6 P05231 interleukin 6 0.32 0.248 0.962
KLF6 Q99612 Kruppel like factor 6 Nucleic acid binding 0.98 0.501 0.846
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
KMT2C Q8NEZ4 lysine methyltransferase 2C 1.00 0.558 0.692
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
M6PR P20645 mannose-6-phosphate receptor, cation dependent Receptor 9.2E-03 0.716 0.269
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846
MT2A P02795 metallothionein 2A 1.2E-05 0.553 0.808
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
PAX6 P26367 paired box 6 1.00 0.450 0.769
PDHA1 P08559 pyruvate dehydrogenase E1 subunit alpha 1 0.99 0.581 0.538