Disease: melanoma
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
APEX1 P27695 apurinic/apyrimidinic endodeoxyribonuclease 1 1.9E-07 0.458 0.846
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
AURKA O14965 aurora kinase A Kinase 0.87 0.475 0.731
BAP1 Q92560 BRCA1 associated protein 1 Enzyme 0.99 0.454 0.731
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CLU P10909 clusterin 7.8E-05 0.426 0.885
CST6 Q15828 cystatin E/M 0.37 0.612 0.615
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CUL3 Q13618 cullin 3 1.00 0.592 0.654
CYP1B1 Q16678 cytochrome P450 family 1 subfamily B member 1 Enzyme 2.2E-05 0.457 0.769
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
FASLG P48023 Fas ligand Signaling 0.18 0.430 0.885
GDF15 Q99988 growth differentiation factor 15 Signaling 3.0E-07 0.429 0.808
HDAC6 Q9UBN7 histone deacetylase 6 Epigenetic regulator 1.00 0.465 0.846
HOXB13 Q92826 homeobox B13 3.7E-08 0.573 0.462
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
HSPA1A P0DMV8 P0DMV9 heat shock protein family A (Hsp70) member 1A 3.0E-02 0.486 0.769
IL2 P60568 interleukin 2 0.48 0.336 0.885
JMJD6 Q6NYC1 jumonji domain containing 6, arginine demethylase and lysine hydroxylase Receptor 0.93 0.615 0.654
LRP1B Q9NZR2 LDL receptor related protein 1B 2.5E-06 0.626 0.615
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846