Disease: Malignant transformation
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
NFKB1 P19838 nuclear factor kappa B subunit 1 Transcription factor 1.00 0.396 0.923
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
NUP98 P52948 nucleoporin 98 and 96 precursor Enzyme 1.00 0.532 0.577
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
MLLT10 P55197 MLLT10 histone lysine methyltransferase DOT1L cofactor Transcription factor 1.00 0.551 0.462
SETD1A O15047 SET domain containing 1A, histone lysine methyltransferase 1.00 0.619 0.615
KMT2C Q8NEZ4 lysine methyltransferase 2C 1.00 0.558 0.692
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PTPN6 P29350 protein tyrosine phosphatase non-receptor type 6 1.00 0.485 0.769
DLL1 O00548 delta like canonical Notch ligand 1 1.00 0.492 0.808
PRDM16 Q9HAZ2 PR/SET domain 16 1.00 0.522 0.808
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
HNRNPK P61978 heterogeneous nuclear ribonucleoprotein K Enzyme 1.00 0.539 0.846