Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885
TNFSF10 P50591 TNF superfamily member 10 Signaling 0.13 0.413 0.885
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
FASLG P48023 Fas ligand Signaling 0.18 0.430 0.885
MMP13 P45452 matrix metallopeptidase 13 Enzyme 7.9E-18 0.452 0.923
COL11A1 P12107 collagen type XI alpha 1 chain 1.00 0.495 0.846
GDF5 P43026 growth differentiation factor 5 Signaling 0.67 0.511 0.692