Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
ACAN | P16112 | aggrecan | Extracellular structure | 1.00 | 0.528 | 0.846 |
ADAMTS3 | O15072 | ADAM metallopeptidase with thrombospondin type 1 motif 3 | Enzyme | 1.0E-10 | 0.581 | 0.808 |
ADAMTS4 | O75173 | ADAM metallopeptidase with thrombospondin type 1 motif 4 | Enzyme | 2.0E-06 | 0.582 | 0.692 |
ADAMTS5 | Q9UNA0 | ADAM metallopeptidase with thrombospondin type 1 motif 5 | Enzyme | 8.0E-07 | 0.597 | 0.654 |
ASPN | Q9BXN1 | asporin | 1.0E-07 | 0.636 | 0.500 | |
CILP | O75339 | cartilage intermediate layer protein | 5.4E-26 | 0.736 | 0.423 | |
COL11A1 | P12107 | collagen type XI alpha 1 chain | 1.00 | 0.495 | 0.846 | |
COL9A2 | Q14055 | collagen type IX alpha 2 chain | 1.0E-08 | 0.572 | 0.769 | |
COL9A3 | Q14050 | collagen type IX alpha 3 chain | 3.3E-12 | 0.569 | 0.769 | |
GDF5 | P43026 | growth differentiation factor 5 | Signaling | 0.67 | 0.511 | 0.692 |
HIF1A | Q16665 | hypoxia inducible factor 1 subunit alpha | Transcription factor | 0.98 | 0.327 | 0.923 |
IL1A | P01583 | interleukin 1 alpha | 1.6E-04 | 0.333 | 0.962 | |
MIR589 | microRNA 589 | 0.656 | 0.538 | |||
MMP13 | P45452 | matrix metallopeptidase 13 | Enzyme | 7.9E-18 | 0.452 | 0.923 |
MMP2 | P08253 | matrix metallopeptidase 2 | Enzyme | 0.84 | 0.333 | 0.923 |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
TIMP1 | P01033 | TIMP metallopeptidase inhibitor 1 | Enzyme modulator | 0.50 | 0.380 | 0.885 |
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
TNFSF10 | P50591 | TNF superfamily member 10 | Signaling | 0.13 | 0.413 | 0.885 |
VDR | P11473 | vitamin D receptor | Nuclear receptor | 1.7E-05 | 0.352 | 0.885 |